I would have to say my least favorite font is Commic Sans.  If I get an email from someone or go to a website with a nice big pink Comic Sans my stomach begins to rumble.  For potential customers to take your business and website seriously stick with professional fonts that are available on everyone’s computer.

I would recommend sticking with the following fonts when creating your website:

I would recommend NOT using this font for your web design:

This article from Sitepoint discusses the art of typography and its graduation to the computer screen.

Keep in mind, it is difficult to know what browser and operating system your users are using so try to keep a font that is accessible to the majority of users.